🧪 Synthetic ADaM Generator

Real ADaM is locked behind BAA agreements and patient consent. For testing, training, or demos you need realistic dummy data with proper CDISC structure - the right ADSL flags, sensible AE severities, realistic lab toxicity grades, valid SOC/PT codes. This service generates all 7 standard ADaM datasets with reproducible seeds and configurable patient counts.

How to use

# Preview as JSON (single dataset)
curl "https://synth.clincoder.cloud/api/generate?kinds=adsl&n_per_arm=25&seed=42"

# Download a ZIP of all 7 datasets as CSV (50 subjects/arm)
curl -X POST "https://synth.clincoder.cloud/api/generate.zip?kinds=adsl,adae,advs,adlb,adtte,adrs,adex&n_per_arm=50&seed=42" -o adam.zip
unzip adam.zip

# Use in R
ds <- read.csv("adsl.csv")
table(ds$arm)

What you get

• ADSL - one row per subject. USUBJID, AGE, SEX, RACE, ARM/ARMCD, TRT01A/TRT01P, RANDDT, TRTSDT, TRTEDT, SAFFL/ITTFL/EFFFL flags.
• ADAE - one row per adverse event. USUBJID, AESEQ, AETERM, AESOC, AEPT, AESEV, AESER, TRTEMFL.
• ADVS - one row per subject-parameter-visit. PARAMCD (SYSBP/DIABP/PULSE), AVAL, BASE, CHG, AVISIT.
• ADLB - one row per subject-parameter-visit. PARAMCD (ALT/AST/BILI/ALP), AVAL, BASE, ATOXGR, BTOXGR.
• ADTTE - one row per subject per endpoint (OS/PFS). AVAL (days), CNSR, EVNTDESC.
• ADRS - one row per subject. AVAL/AVALC for best response (CR/PR/SD/PD/NE).
• ADEX - one row per dose. EXSEQ, EXDOSE, EXSTDTC, EXENDTC.

All datasets cross-link via USUBJID. ARM/treatment is consistent across datasets. Seeded for reproducibility.

Pricing